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. 2020 Jun 29;148:e159. doi: 10.1017/S0950268820001387

Table 5.

Amino acid substitutions of the NA protein in Hulunbuir (H1N1) pdm09 strains compared with that in A/Michigan/45/2015, the WHO-recommended vaccine strain during 2017–2019

Year Strains %AA identity NA
14 41 47 51 74 77 81 127 163 188 248 314 389 416 438 449 452 453 467
A/Michigan/45/2015(H1N1) 100.00 C G E Q F G V L I I D M I D T N T V I
2017 A/Hulunbuir/1701/2017(H1N1) 99.57 G T
2017 A/Hulunbuir/1702/2017(H1N1) 99.79 D
2017 A/Hulunbuir/1703/2017(H1N1) 99.79 D
2018 A/Hulunbuir/1801/2017(H1N1) 97.23 R A V T N D G
2018 A/Hulunbuir/1802/2017(H1N1) 98.72 R A V T N D
2018 A/Hulunbuir/1803/2017(H1N1) 98.93 R A T A D
2019 A/Hulunbuir/1901/2017(H1N1) 98.08 K S R A T K N D I
2019 A/Hulunbuir/1902/2017(H1N1) 98.08 K S R A T K N D I
2019 A/Hulunbuir/1903/2017(H1N1) 98.51 S R A V I D V

Notes: 2009 H1N1 pandemic numbering.