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. 2020 Jun 22;29(14):2337–2352. doi: 10.1093/hmg/ddaa124

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Restoring Lztfl1 expression at an advanced stage (P90–94) has little therapeutic effect. (A and B) Immunoblot analyses of P90-treated Lztfl1^gt/gt;FLP⁺ mice at 1 month (A) and 3 months (B) PTI. (C) STX3 and STXBP1 localization in P90-treated Lztfl1^gt/gt;FLP⁺ mice. Scale bar: 25 μm. (D) Survival of cones in P90-treated Lztfl1^gt/gt;FLP⁺ mice. (E) ERG responses of Lztfl1^gt/gt;FLP⁺ mice treated at P90–94. Others are the same as in Figure 3.