Fig. 6.

Representative sections from pancreas and liver of healthy and STZ-induced diabetic rats. Eosin-hematoxylin stain, 200x. A. Pancreatic section of healthy animal shows a well-preserved cellular architecture. The islets of Langerhans exert a homogenous morphology of β-cells (arrow). B. Pancreatic section of STZ-induced diabetic rat shows degranulation and vacuolation of β-cells (arrow). C, D. Liver sections from healthy (C) and diabetic (D) animals demonstrate normal architecture of the liver parenchyma without evidence of portal inflammation or necrosis.