TABLE 1.
Patient characteristics of kidney transplant recipients with primary glomerular disease as the cause of ESRD
| IgA (N = 306) |
FSGS (N = 298) |
MN (N = 81) |
LN (N = 177) |
P-value | |
|---|---|---|---|---|---|
| Age (y), mean | 42.8 | 44.9 | 50.5 | 42.8 | <.005 |
| Sex, N (%) | 212 (69) | 184 (62) | 55 (68) | 38 (22) | <.05 |
| Male | |||||
| Race, N (%) | 259 (84) | 233 (78) | 71 (88) | 140 (79) | .07 |
| Caucasian | |||||
| BMI (kg/m2), mean | 27.4 | 27.6 | 27.0 | 25.1 | .05 |
| Duration of disease prior to transplant (y), mean | 7.1 | 7.6 | 7.5 | 8.3 | .03 |
| Dialysis duration prior to transplant (y), mean | 1.2 | 2.0 | 1.7 | 2.4 | <.005 |
| Prior transplant, % | 17 | 22 | 26 | 25 | .15 |
| Peak PRA, % | 5.9 | 10.2 | 15.3 | 18.3 | .005 |
| HLA mismatch | |||||
| Mismatch >2, % | 79 | 83 | 75 | 72 | |
| HLA A, % | 75 | 78 | 65 | 65 | .005 |
| HLA B, % | 79 | 83 | 74 | 70 | .006 |
| HLA DR, % | 69 | 72 | 72 | 64 | .41 |
| Donor type | |||||
| Deceased, % | 41 | 65 | 61 | 57 | .005 |
| Age (y), mean | 41.5 | 41.7 | 40.2 | 40.1 | .58 |
| Male, % | 48 | 57 | 52 | 50 | .15 |
| Caucasian, % | 94 | 93 | 93 | 91 | .53 |
| Cold ischemia time (h), mean | 16 | 22 | 20 | 29 | .46 |
| Delayed graft function, % | 10 | 21 | 14 | 17 | .01 |
| Maintenance IS | |||||
| Prednisone, % | 100 | 100 | 100 | 100 | NA |
| Calcineurin inhibitor, % | 94 | 87 | 91 | 94 | .01 |
| Mycophenolate, % | 89 | 89 | 85 | 89 | .81 |
Abbreviations: FSGS, focal segmental glomerulosclerosis; IgA, IgA nephropathy; LN, lupus nephritis; MN, membranous nephropathy.