Table 2.
Factors and covariates associated with a diagnosis of specific EAM in patients with axSpA (multivariable models)
| Parameter | B | SE | P value | Incidence rate ratio (IRR) |
95% CI for IRR |
|---|---|---|---|---|---|
| A. Diagnosis of AUU | |||||
| (Intercept) | −2.370 | 0.2788 | <0.001 | 0.093 | 0.054–0.161 |
| HLA-B27 positive (vs negative) | 0.669 | 0.1710 | <0.001 | 1.953 | 1.396–2.730 |
| University degree (vs lower) | 0.165 | 0.1507 | 0.273 | 1.179 | 0.878–1.585 |
| Ever-smoking (vs never) | −0.349 | 0.1322 | 0.008 | 0.706 | 0.545–0.915 |
| Age (years) | 0.009 | 0.0053 | 0.093 | 1.009 | 0.999–1.019 |
| axSpA disease duration (years) | 0.005 | 0.0050 | 0.305 | 1.005 | 0.995–1.015 |
| B. Diagnosis of Psoriasis | |||||
| (Intercept) | −3.069 | 0.592 | 0.000 | 0.046 | 0.015–0.148 |
| HLA-B27 positive (vs negative) | −0.621 | 0.197 | 0.002 | 0.538 | 0.365–0.791 |
| University degree (vs lower) | 0.326 | 0.283 | 0.248 | 1.386 | 0.796–2.412 |
| Ever-smoking (vs never) | 0.256 | 0.228 | 0.262 | 1.292 | 0.826–2.020 |
| Age (years) | 0.009 | 0.007 | 0.173 | 1.009 | 0.996–1.022 |
| BMI (kg/m2) | 0.022 | 0.016 | 0.155 | 1.023 | 0.992–1.05 |
| C. Diagnosis of IBD | |||||
| (Intercept) | −2.698 | 0.3617 | <0.001 | 0.067 | 0.033–0.137 |
| HLA-B27 positive (vs negative) | −0.466 | 0.1894 | 0.014 | 0.627 | 0.433–0.909 |
| Age (years) | 0.012 | 0.0079 | 0.128 | 1.012 | 0.997–1.028 |
| axSpA disease duration (years) | 0.003 | 0.0078 | 0.671 | 1.003 | 0.988–1.019 |
AAU, acute anterior uveitis; axSpA, axial spondyloarthritis; BMI, body mass index; EAM, extra-articular manifestation; HLA, human leukocyte antigen; IBD, inflammatory bowel disease.