Table 2.
Variable distributions: results from the analysis of primary and secondary outcomes
| Decision aid (n = 68) Mean (SD) |
Genetic counselor (n = 65) Mean (SD) |
Intervention vs. control Between group difference (95% CI) |
Significance |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | After DA (T1) | After DA + GC (T2) | Baseline | After GC (T1) | T1 vs. T1 | T2 vs. T1 | T1 vs. T1 | T2 vs. T1 | |
| Decisional conflict (1–5) | – | 1.87 (0.71) | 1.77 (0.69) | – | 1.71 (0.54) | 0.15 (−0.06 to 0.36) | 0.05 (−0.15 to 0.27) | 0.16 | 0.60 |
| Decisional conflict adjusted score (0–100) | – | 21.67 (17.77) | 19.25 (17.16) | 17.84 (13.51) | −3.83 (−9.23 to 1.57) | −1.41 (−6.75 to 3.93) | 0.16 | 0.60 | |
| Knowledge of secondary findings (0–5) | – | 4.92 (0.32) | 4.93 (0.26) | – | 4.54 (0.81) | – | 0.39 (0.18 to 0.59) | – | <0.001 |
| Knowledge: sequencing limitations (1–10) | 5.85 (2.53) | 7.32 (2.53) | 7.41 (2.46) | 5.75 (2.74) | 7.14 (2.74) | 0.12 (−0.67 to 0.86) | 0.14 (−0.61 to 0.89) | 0.73 | 0.70 |
| Knowledge: sequencing benefits (1–10) | 5.12 (2.00) | 7.07 (2.19) | 7.06 (2.12) | 5.08 (1.97) | 6.09 (2.47) | 1.00 (0.26 to 174) | 0.97 (0.22 to 0.95) | 0.01 | 0.01 |
| Preparation for decision-making (0–100) | – | 74.38 (17.46) | 76.06 (16.74) | – | 76.23 (18.44) | 1.86 (−4.31 to 8.02) | 0.17 (−5.92 to 6.26) | 0.55 | 0.95 |
| Satisfaction with decision (6–30) | – | 21.79 (7.95) | 24.55 (5.54) | – | 22.37 (7.71) | 0.58 (−2.11 to 3.26) | −2.18 (−4.5 to 0.15) | 0.60 | 0.06 |
| State-Trait Anxiety Inventory (20–80) | 28.97 (11.16) | 27.90 (9.72) | 26.06 (9.14) | 31.02 (12.45) | 27.03 (9.64) | 2.22 (−0.34 to 4.79) | 0.72 (−1.73 to 3.18) | 0.89 | 0.56 |
| Time with genetic counselor (minutes) | – | – | 16.15 (9.20) | – | 40.55 (9.11) | 24.40 (27.72 to −21.07) | <0.001 | ||
CI confidence interval, DA decision aid, GC genetic counseling.