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. 2020 Aug 13;26:78. doi: 10.1186/s10020-020-00208-9

Fig. 4.

Fig. 4

ARID1A or ARID1B mutations are tightly associated with sensitivity to immune checkpoint inhibitors (ICIs). a. The comparison of tumor mutational burden (TMB) values and PD-L1 expression grouped by the genomic signatures of ARID1 subunits; b. The correlations between ARID1A or ARID1B expression and the abundances of activated CD8+ T cells and activated dendritic cells (DC) in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC); c. The underlying relationships between prognosis and ARID1A or ARID1B mutation deduced from this research. (**: P<0.01; *: P<0.05)