Table 2.
Change of the functional parameters of the retina according to study timepoints
| Patient No. | Eye | BCVA | FPDI | ERG amplitudes | ERG implicit times | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T0 | T1 | T2 | T0 | T1 | T2 | T0 | T1 | T2 | T0 | T1 | T2 | ||
| 1 | R | 100 | 110 | 110 | 5 | 11 | 12 | 3.2 | 6.3 | 6.4 | 43.8 | 38.8 | 38.7 |
| 2 | L | 80 | 87 | 90 | 6 | 16 | 19 | 2.1 | 2.3 | 2.6 | 42.7 | 42.7 | 40.8 |
| 3 | R | 80 | 88 | 88 | 10 | 12 | 12 | 1.5 | 3.0 | 2.9 | 42.3 | 40.7 | 40.4 |
| 4 | L | 84 | 88 | 91 | 6 | 10 | 11 | 1.9 | 4.1 | 4.0 | 40.3 | 40.0 | 39.9 |
| 5 | L | 50 | 74 | 50 | 4 | 7 | 5 | 2.4 | 11.1 | 2.6 | 47.4 | 42.5 | 46.3 |
| 6 | L | 80 | 85 | 85 | 7 | 13 | 14 | 3.6 | 19.7 | 19.9 | 50.0 | 50.0 | 49.8 |
| 7 | R | 50 | 56 | 60 | 15 | 22 | 23 | 1.6 | 2.7 | 2.8 | 50.0 | 50.0 | 49.8 |
| 8 | L | 80 | 87 | 87 | 5 | 7 | 7 | 1.4 | 2.4 | 2.3 | 50.0 | 46.1 | 45.8 |
| 9 | L | 72 | 79 | 79 | 8 | 14 | 14 | 2.0 | 2.5 | 2.6 | 44.6 | 42.1 | 42.0 |
| 10 | L | 50 | 55 | 55 | 14 | 19 | 18 | 4.4 | 6.0 | 5.8 | 38.5 | 34.9 | 35.0 |
| 11 | R | 65 | 77 | 77 | 5 | 10 | 9 | 1.0 | 4.1 | 3.8 | 44.1 | 35.7 | 36.0 |
| 12 | R | 65 | 74 | 74 | 4 | 8 | 8 | 11.0 | 16.9 | 16.3 | 26.9 | 26.7 | 26.8 |
| 13 | L | 65 | 87 | 87 | 5 | 9 | 10 | 1.4 | 7.4 | 7.6 | 43.4 | 22.8 | 22.4 |
| 14 | R | 50 | 69 | 70 | 14 | 26 | 26 | 2.8 | 3.9 | 4.0 | 38.6 | 34.0 | 39.9 |
| 15 | L | 89 | 110 | 110 | 4 | 16 | 16 | 2.0 | 2.7 | 2.8 | 38.1 | 38.0 | 37.8 |
| 16 | R | 80 | 83 | 77 | 5 | 5 | 4 | 0.9 | 1.3 | 0.9 | 49.1 | 34.1 | 42.9 |
| 17 | L | 50 | 59 | 60 | 6 | 6 | 7 | 1.7 | 4.0 | 4.0 | 32.8 | 23.5 | 24.0 |
| 18 | L | 80 | 85 | 85 | 10 | 12 | 12 | 1.5 | 8.9 | 8.8 | 34.8 | 22.5 | 23.5 |
| 19 | R | 50 | 65 | 65 | 14 | 15 | 15 | 1.3 | 4.9 | 4.9 | 40.8 | 32.1 | 32.7 |
| 20 | R | 60 | 77 | 77 | 10 | 12 | 13 | 1.6 | 1.8 | 2.0 | 49.2 | 49.2 | 49.0 |
| 21 | R | 50 | 59 | 60 | 4 | 5 | 5 | 1.5 | 1.8 | 1.8 | 44.0 | 44.0 | 43.8 |
| 22 | L | 77 | 87 | 87 | 8 | 10 | 11 | 2.6 | 3.0 | 3.0 | 46.0 | 43.5 | 43.8 |
| 23 | R | 70 | 70 | 70 | 10 | 10 | 10 | 5.0 | 5.1 | 5.0 | 48.2 | 48.2 | 48.0 |
| 24 | L | 98 | 110 | 110 | 7 | 10 | 11 | 1.5 | 2.7 | 2.7 | 39.6 | 24.4 | 24.2 |
| 25 | L | 85 | 91 | 91 | 10 | 16 | 18 | 1.4 | 1.9 | 2.1 | 35.7 | 29.0 | 29.0 |
| 26 | L | 89 | 110 | 110 | 7 | 10 | 10 | 5.0 | 8.9 | 8.7 | 41.6 | 35.2 | 35.2 |
| 27 | R | 85 | 94 | 94 | 10 | 12 | 12 | 2.0 | 2.8 | 2.9 | 48.2 | 46.8 | 46.0 |
| 28 | R | 50 | 55 | 50 | 4 | 4 | 4 | 1.8 | 9.6 | 3.6 | 46.0 | 34.0 | 39.0 |
| 29 | R | 50 | 50 | 50 | 5 | 5 | 5 | 2.8 | 6.6 | 4.8 | 39.5 | 39.5 | 39.3 |
| 30 | L | 89 | 94 | 94 | 6 | 8 | 8 | 0.7 | 2.9 | 2.8 | 48.8 | 36.6 | 37.0 |
| 31 | R | 74 | 85 | 85 | 15 | 16 | 16 | 1.6 | 3.3 | 3.2 | 48.2 | 44.1 | 44.0 |
| L | 80 | 87 | 87 | 14 | 15 | 15 | 2.0 | 2.8 | 2.8 | 47.4 | 43.2 | 43.2 | |
| 32 | R | 60 | 77 | 77 | 8 | 11 | 11 | 1.9 | 2.0 | 2.0 | 44.0 | 36.0 | 37.0 |
| L | 60 | 77 | 77 | 7 | 10 | 10 | 1.5 | 1.7 | 1.7 | 47.0 | 38.0 | 39.0 | |
BCVA best corrected visual acuity (ETDRS letters), FPDI fundus perimetry deviation index (%), ERG amplitudes full-field flicker electroretinography amplitudes (mV), ERG implicit times full-field flicker electroretinography implicit times (ms), T0 (baseline) just before the Wharton jelly-derived mesenchymal stem cell injection, T1 6th month after injection, T2 12th month after injection