Table 4.
Comparison of functional measurements according to inheritance pattern
| Inheritance | BCVA | FPDI | ||||
|---|---|---|---|---|---|---|
| T0 | T2 | p | T0 | T2 | p | |
| AD n = 12 | 81.8 ± 11.8 | 91.6 ± 12.2 | 0.01* | 8.9 ± 2.7 | 13.2 ± 2.9 | 0.01* |
| AR n = 16 | 61.7 ± 10.9 | 72.9 ± 10.5 | 0.01* | 8.1 ± 2.7 | 11.7 ± 2.7 | 0.01* |
| X-linked n = 2 | 65.0 ± 0 | 63.5 ± 0 | 0.09 | 4.5 ± 0 | 4.5 ± 0 | 0.1 |
| Comparison** | pAR = pAD > pX-linked | pAD > pAR > pX-linked | ||||
**Sidak binary comparison test; *p < 0.05, statistically significant
AD autosomal dominant, AR autosomal recessive, X-linked X-related inheritance pattern, BCVA best corrected visual acuity (ETDRS letters), FPDI fundus perimetry deviation index (%), T0 (baseline) just before the Wharton jelly-derived mesenchymal stem cell injection, T2 12th month after injection