Table 4.
Performance of simplified ELN-2017 risk stratification criteria
| Covariates | Discovery | Validation |
|---|---|---|
| Complete Response (CR, AUC) | ||
| ELN2017 | 0.65 | 0.74 |
| AGE + ELN2017 | 0.71 | 0.76 |
| ELN2017-MOD | 0.65 | 0.72 |
| AGE + ELN2017-MOD | 0.71 | 0.77 |
| Overall Survival (OS, C Statistic) | ||
| ELN2017 | 0.60 | 0.68 |
| AGE + ELN2017 | 0.71 | 0.73 |
| ELN2017-MOD | 0.60 | 0.67 |
| AGE + ELN2017-MOD | 0.72 | 0.73 |
| Relapse-Free Survival (RFS, C Statistic) | ||
| ELN2017 | 0.64 | 0.62 |
| AGE + ELN2017 | 0.68 | 0.67 |
| ELN2017-MOD | 0.62 | 0.63 |
| AGE + ELN2017-MOD | 0.67 | 0.68 |
Comparison of predictive value of ELN2017 and ELN2017-MOD and change in predictive value with the addition of age as a covariate