Table 2.
Baseline and 8-week body composition and fat distribution outcomes by diet group
| LFD | VLCD |
P for diet |
P for diet adjusted for change in total fat |
|||
|---|---|---|---|---|---|---|
| Week 0 | Week 8 | Week 0 | Week 8 | |||
| Weight (kg) | 96.8 ± 30.9 | 95.9 ± 28.4 | 93.7 ± 15.1 | 87.8 ± 12.5*** | < 0.001 | 0.41 |
| Total fat (kg) | 40.3 ± 7.5 | 39.5 ± 7.5* | 42.4 ± 9.6 | 38.3 ± 10.9*** | < 0.001 | – |
| VAT (kg) | 1.8 ± 0.8 | 1.7 ± 0.8 | 2.2 ± 1.0 | 1.7 ± 0.7*** | < 0.01 | .99 |
| VAT (cm3) | 2077.6 ± 1038 | 2145.4 ± 1056.8 | 2613.6 ± 943.5 | 2249.2 ± 778.2** | 0.01 | 0.58 |
| SAAT (cm3) | 5496.8 ± 2049 | 5116.8 ± 2117.3 | 5481.1 ± 2499.3 | 4340.9 ± 1626** | 0.05 | 0.15 |
| Thigh SAT (cm3) | 349.6 ± 225.5 | 346.2 ± 216.1 | 317.2 ± 199.7 | 289.6 ± 186.4** | 0.08 | 0.91 |
| Thigh PMAT (cm3) | 36.2 ± 16.2 | 36.4 ± 18.3 | 33.8 ± 11.3 | 30.9 ± 13.8 | 0.13 | 0.46 |
| Thigh IMAT (cm3) | 15.1 ± 6.6 | 15.7 ± 8.7 | 20.9 ± 13.4 | 15.8 ± 9.9*** | < 0.01 | 0.02 |
| Thigh SM (cm3) | 345.9 ± 78.8 | 339.4 ± 76.3 | 366.5 ± 95.2 | 354.3 ± 84.9 | 0.67 | 0.02 |
| Total lean (kg) | 47.3 ± 7.2 | 48.0 ± 6.9 | 50.3 ± 1.2 | 48.8 ± 1.2** | 0.01 | 0.07 |
Data presented as mean ± SD
*p < 0.05, **p < 0.01, ***p < 0.001 for paired t-test; P for effect of diet, results from ANCOVA (8-week outcome adjusted for baseline); P for the effect of diet, results from ANCOVA (8-week outcome adjusted for baseline and change in fat mass); VAT visceral adipose tissue, SAAT subcutaneous abdominal adipose tissue, IMAT intermuscular adipose tissue, PMAT perimuscular adipose tissue, SAT subcutaneous adipose tissue, SM skeletal muscle