Figure 1.
Prospective follow-up of 45 patients with adolescent/adult ALD and enrolment for HSCT. Forty-five male patients with ALD were enrolled in this study in a prospective manner from September 29, 2003, to October 31, 2018. Among them, 25 patients were considered for HSCT on the basis of detection of MRI lesions in the cerebrum, cerebellum or brainstem. HSCT was conducted on 12 patients. We did not conduct HSCT on eight patients because five patients were in advanced stages (Patients 13, 14, 16, 17 and 19) and three declined to undergo HSCT (Patients 15, 18 and 20). CB = cerebello-brainstem form of ALD; AMN-CB = AMN with later development of cerebello-brainstem form of ALD. aOne patient with AMN died of a brain haemorrhage.
