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. 2020 Jan 29;2(1):fcaa006. doi: 10.1093/braincomms/fcaa006

Table 3.

Clinical outcomes of non-screened and screened classical patients

N Classical non-screened patients (n = 32) n Classical screened patients (n = 15) P-value
Gender 32 15
 Male 17 6 0.534
 Female 15 9
Age (years) 32 24.5 (11–48) 15 10.0 (4–32) 0.002
 Paediatric patients (<18 years) 9 10 0.024
 Adult patients (≥18 years) 23 5
GALT activity (%) 30 15
 <3.3 29 15 1.000
 ≥3.3 1
IQ 26 78.0 (45–103) 14 71.0 (52–95) 0.421
 IQ < 85 16 10 1.000
 Q ≥ 85 10 4
Neurology 19 10
 MDs, no 6 6 0.236
 Ds, yes 13 4
TRS 15 6.0 (0–38) 3 10.0 (4–34) 0.311
DRS 15 0.0 (0–6) 3 1.0 (0–2) 0.104
Endocrinology (females ≥ 12 years) 14 5
Puberty induced, no 7 2 0.620
Puberty induced, yes 5 3
 POI, no 2 1 1.000
 POI, yes 9 3
Gal-1-P (μmol/g Hb) in erythrocytesa 28 0.36 (0.24–0.62) 15 0.40 (0.16–0.70) 0.221
Galactitol (mmol/mol creatinine) in urinea 14 128 (109–168) 11 175 (113–311) 0.204

Data reported in median and ranges.

a

Most recent value is presented.

IQ: intelligence quotient; TRS: tremor rating scale; DRS: dystonia rating scale.

Bold numbers defining as statistically significant.