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. 2020 Jul 16;12(14):14406–14417. doi: 10.18632/aging.103484

Figure 2.

Figure 2

Effect of PTEN on regulating the cisplatin sensitivity of CD133+ and CD133- HCC cells. (A) expression of PTEN in CD133+ and CD133- Huh7 and HepG2 cells. &P<0.05 vs. CD133- Huh7 cells, #P<0.05 vs. CD133- HepG2 cells. (B) Transfection with PTEN plasmid increased the expression of PTEN in CD133+ Huh7 and HepG2 cells. *P<0.05. (C) Transfection with PTEN plasmid increased the sensitivity of CD133+ Huh7 and HepG2 cells to cisplatin (5 μM) treatment. *P<0.05. (D) Transfection with PTEN siRNA decreased the expression of PTEN in CD133- Huh7 and HepG2 cells. *P<0.05. (E) Transfection with PTEN siRNA decreased the sensitivity of CD133- Huh7 and HepG2 cells to cisplatin (5 μM) treatment. *P<0.05.