Table 1. Combination index (CI) with cisplatin and osthole in CD133+ Huh7.
Cisplatin single treatment | Osthole single treatment | Combination treatment | Combination index (CI) | ||
Concentration (μM) | Inhibitory rate (%) | Concentration (μM) | Inhibitory rate (%) | Inhibitory rate (%) | |
1 | 2.1 | 2 | 3.8 | 20.4 | 3.51 |
2 | 4.4 | 4 | 4.9 | 32.6 | 3.59 |
5 | 8.7 | 10 | 6.3 | 55.2 | 3.82 |
10 | 16.5 | 20 | 8.8 | 62.8 | 2.63 |
15 | 22.7 | 30 | 12.6 | 67.6 | 2.08 |
20 | 28.8 | 40 | 14.5 | 73.4 | 1.88 |
30 | 37.9 | 60 | 16.3 | 79.5 | 1.66 |