Table 1. Demographics and clinicopathologic characteristics of patients with HSNCC.
| Variables | Training cohort (N = 115) | Validation cohort (N = 56) | ||
| N | % | N | % | |
| Gender | ||||
| Male | 100 | 86.96 | 47 | 83.93 |
| Female | 15 | 13.04 | 9 | 16.07 |
| Age (years) | ||||
| 60 | 71 | 61.74 | 30 | 53.57 |
| ≥ 60 | 44 | 38.26 | 26 | 46.43 |
| Tumor size | ||||
| ≤ 4 | 94 | 81.74 | 27 | 48.21 |
| 4 | 57 | 49.57 | 29 | 51.79 |
| Tumor Location | ||||
| Oropharynx | 92 | 80.00 | 47 | 83.93 |
| Larynx | 13 | 11.30 | 6 | 10.71 |
| Oral cavity | 2 | 1.74 | 2 | 3.57 |
| Hypopharynx | 8 | 6.96 | 3 | 5.36 |
| Differentiation status | ||||
| Well | 13 | 11.30 | 4 | 7.14 |
| Moderate | 51 | 44.35 | 28 | 50.00 |
| Poor and undifferentiated | 51 | 44.35 | 24 | 42.86 |
| T stage * | ||||
| T1 | 21 | 18.26 | 10 | 17.86 |
| T2 | 37 | 32.17 | 17 | 30.36 |
| T3 | 34 | 29.57 | 18 | 32.14 |
| T4 | 23 | 20.00 | 11 | 19.64 |
| N stage * | ||||
| N0 | 10 | 8.70 | 9 | 16.07 |
| N1 | 11 | 9.57 | 8 | 14.29 |
| N2a | 5 | 4.35 | 4 | 7.14 |
| N2b | 56 | 48.70 | 19 | 33.93 |
| N2c | 28 | 24.35 | 9 | 16.07 |
| N3 | 5 | 4.35 | 7 | 12.50 |
| TNM stage * | ||||
| I | 1 | 0.87 | 0 | 0.00 |
| II | 2 | 1.74 | 3 | 5.36 |
| III | 15 | 13.04 | 13 | 23.21 |
| IVA | 90 | 78.26 | 32 | 57.14 |
| IVB | 7 | 6.09 | 8 | 14.29 |
* according to 7th AJCC stage system.
Abbreviation: HSNCC-head and neck squamous cell carcinoma; N-number.