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. 2020 Jul 20;12(14):14933–14948. doi: 10.18632/aging.103553

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Copyright © 2020 Wu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Pan-cancer mRNA and protein expression of FRGs. (A) Box plots show SLC7A11 mRNA expression in tumor (red) and normal (blue) tissue samples corresponding to 33 cancer types. Note: **P<0.01; ***P<0.001. (B) Alterations in the expression of 36 FRGs in 20 different cancer types are shown with the color code bar (right) referring to the corresponding log2 (FC) values. (C) Box plots show the differences in the expression of 18 different ferroptosis-related proteins in the KIRC (blue) and normal kidney (orange) tissues from the UALCAN dataset. (D) The overall survival of patients belonging to 33 cancer types based on the expression of the 36 FRGs is shown. The color code is shown in the right.