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. 2019 Sep 14;1(1):fcz018. doi: 10.1093/braincomms/fcz018

Figure 2.

Figure 2

Risk of poor outcomes after ICH, based on APOE genotype and hypertension severity during follow-up. (A) Kaplan–Meier estimates of risk for composite poor post-ICH outcome, including: (i) recurrent ICH; (ii) ischaemic stroke (all subtypes); (iii) incident dementia; (iv) incident depression; and (v) incident gait impairment. Risk distributions are separated based on APOE genotype (ε4: 0 copies versus 1–2 copies) and hypertension severity during follow-up. P-values are calculated for each group in reference to normotensive subjects (regardless of APOE genotype) using the Log-rank test. (B) Estimates of yearly risk for individual post-ICH outcomes of interest, stratified by APOE genotype (ε4: 0 copies versus 1–2 copies) and hypertension severity during follow-up. Vertical error bars indicate one standard deviation in risk estimate. Single asterisk indicates P-value < 0.05 for comparison with normotensive subjects (regardless of APOE genotype) using the Log-rank test. Double asterisks indicate P-value < 0.01 for comparison with normotensive subjects (regardless of APOE genotype) using the Log-rank test. ICH = intracerebral haemorrhage; SV = small vessel.