. Author manuscript; available in PMC: 2021 Mar 1.

Published in final edited form as: J Mol Cell Cardiol. 2020 Feb 11;140:1–9. doi: 10.1016/j.yjmcc.2020.02.004

Table 6.

Purinergic receptor-mediated vascular function in other vascular beds.

Organ	Species	Diabetic model	Nucleot(s)ide/stimuli	Purinergic receptor	Vascular effect	Reference
Cerebral artery	Mouse	Hyperglycemia	Glucose	P2Y₁₁R	Vascular contraction↑	[71]
Pancreas	Rat	STZ	ADO		Vascular flow rate↓	[72]
Tail artery	Rat	STZ	ATP/Electrical stimulation	P2XR	Contraction↑	[74]
Skin	Human	Type 2 diabetes	ATP		Vascular conductance↓	[73]
Muscle arteriole	Hamster	RBC from patients with type 2 diabetes	Decreased ATP release under hypoxia		Vascular relaxation↓	[88,90]

ADO: adenosine; RBC: red blood cells; STZ: streptozotocin; ↑: increased effect; ↓: decreased effect.