Table 3.

Multivariable Cox Proportional Hazards Models for Overall Survival.

Characteristics	Without Propensity Score		Propensity Score-Adjusted
	Hazard of Death (95% CI)	P Value	Hazard of Death (95% CI)	P Value
Thoracic radiotherapy dose
< 45 Gy	Reference		Reference
≥45 Gy	0.78 (0.72–0.84)	< 0.001	0.74 (0.69–0.80)	< 0.001
Gender
Male	Reference		Reference
Female	0.83 (0.77–0.90)	< 0.001	0.82 (0.76–0.88)	< 0.001
Age
< 65	Reference		Reference
≥65	1.28 (1.17–1.40)	< 0.001	1.24 (1.13–1.35)	< 0.001
Comorbid (Charlson-Deyo)
0	Reference		Reference
1	1.19 (1.01–1.30)	< 0.001	1.20 (1.10–1.31)	< 0.001
2 or higher	1.24 (1.10–1.39)	< 0.001	1.21 (1.08–1.37)	< 0.001
Insurance
Uninsured	Reference		Reference
Government	1.10 (0.92–1.15)	0.30	1.03 (0.86–1.25)	0.74
Private	0.99 (0.82–1.19)	0.88	0.93 (0.77–1.12)	0.45
Population
Metro	Reference		Reference
Urban	1.05 (0.95–1.15)	0.37	1.06 (0.96–1.17)	0.25
Rural	1.20 (0.98–1.46)	0.08	1.23 (1.01–1.52)	0.04
Timing of chest radiotherapy
Prior to/first cycle of CTX	Reference
< 12 weeks of starting CTX	0.94 (0.85–1.04)	0.23
≥12 weeks of starting CTX	0.79 (0.71–0.87)	< 0.001
Brain metastases
No	Reference
Yes	1.31 (1.14–1.52)	< 0.001
Liver metastases
No	Reference
Yes	1.61 (1.38–1.87)	< 0.001
Bone metastases
No	Reference
Yes	1.55 (1.34–1.80)	< 0.001
Clinical N stage
N0/N1	Reference
N2	1.08 (0.96–1.21)	0.21
N3	1.22 (1.08–1.38)	0.002

LEGEND: Gy, Gray. CI, confidence interval. CTX, chemotherapy.

Bold indicates statistical significance.