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MicroRNA (miRNA) profile in Lean and MetS MSC-EVs in pigs. Heat map showing four upregulated (top) and four downregulated (bottom) miRNAs in MetS compared with Lean MSC-EVs in pigs. Enrichment of functional pathway of the 68 senescence genes targeted by dysregulated pig miRNAs detected using DAVID 6.7. Expression of miR-132, miR-199a-5p, and miR-99b assessed by qPCR was concordant with miRNA-seq findings in pigs
