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. 2020 Aug 7;14:3223–3234. doi: 10.2147/DDDT.S257613

Figure 4.

Figure 4

Effect of HIR on production of pro-inflammatory cytokines in renal tissues. (AC) qPCR analysis of the indicated TNF-α (A), IL-1β (B), and IL-6 (C) mRNA in renal tissues of rats; (DF) ELISA assay of the indicated TNF-α (D), IL-1β (E), and IL-6 (F) protein in renal tissues of rats. Seven rats per group. *Indicates P < 0.05 and ***indicates P < 0.001 vs control group; #indicates P < 0.05 and ###indicates P < 0.001 vs DN group.