Table 1.
Demographic Characteristics of the Study Subjects
| Groups | |||||
|---|---|---|---|---|---|
| Variables | (A) NAION Eyes (N = 48) | (B) NTG Eyes (N = 48) | (C) Healthy Eyes (N = 48) | P * | Post Hoc† |
| Age at diagnosis (y) | 60.8 ± 9.1 | 60.3 ± 9.2 | 61.7 ± 10.0 | 0.773 | — |
| Female gender, n (%) | 20 (41.67) | 23 (47.92) | 28 (58.33) | 0.256 | — |
| Diabetes mellitus, n (%) | 10 (20.83) | 5 (10.42) | 9 (18.75) | 0.350 | — |
| Hypertension, n (%) | 25 (52.08) | 15 (31.25) | 14 (29.17) | 0.037 | A > B, C |
| IOP at OCT scan (mm Hg), mean ± SD | 12.1 ± 2.8 | 12.5 ± 2.2 | 11.9 ± 2.0 | 0.442 | — |
| Refractive error (D), mean ± SD | –0.11 ± 1.98 | –0.68 ± 1.80 | 0.02 ± 1.32 | 0.115 | — |
| Central corneal thickness (µm), mean ± SD | 545.5 ± 24.7 | 546.4 ± 31.7 | 548.7 ± 27.8 | 0.853 | — |
| Axial length (mm), mean ± SD | 23.42 ± 0.88 | 23.57 ± 0.82 | 23.52 ± 0.82 | 0.700 | — |
| Involved hemifield, n (%) | — | ||||
| Superior | 44 (91.67) | 44 (91.67) | — | — | — |
| Inferior | 4 (8.33) | 4 (8.33) | — | — | — |
| RNFL thickness of the sector of interest‡ (µm), mean ± SD | 68.0 ± 20.9 | 66.5 ± 18.5 | 135.5 ± 12.9 | <0.001 | C > A, B |
| Visual field mean deviation (dB), mean ± SD | –11.64 ± 8.87 | –10.16 ± 6.23 | -0.81 ± 1.47 | <0.001 | C > A, B |
| Visual field pattern standard deviation (dB), mean ± SD | 8.90 ± 4.47 | 8.56 ± 4.47 | 1.77 ± 0.70 | <0.001 | C > A, B |
| Optic disc area (mm2), mean ± SD | 2.14 ± 0.33 | 2.15 ± 0.29 | 2.12 ± 0.34 | 0.903 | — |
| Average BMO width (µm), mean ± SD | 1358.9 ± 125.3 | 1403.9 ± 149.2 | 1396.1 ± 136.7 | 0.233 | — |
Factors with statistical significance are shown in bold.
*
χ2 tests for categorical variables and one-way ANOVA with Bonferroni's post hoc analysis for continuous variables.
†
χ2 tests for categorical variables and Student's t-test for continuous variables.
‡
Determined based on the more severely affected sector.