Differential gene expression patterns induced by butaprost during normal ocular growth. Significant gene expression changes, presented as fold changes, were observed in cAMP-related (A), PPAR/RXR-related (B), hypoxia-related (C), and ECM-related (D) genes in response to butaprost injections. Gene expression data of “N+DMSO” group are provided for visual comparison of the effect of vehicle and drug injections, with the other experimental conditions being the same (*P < 0.05, paired sample t-test).