Table 2.
Pathogens With Positive Rate Over 10% Across All Meibum Samples
| Pathogen | Total Meibum Samples (n = 58) | MGD (n = 47) | HC (n = 11) | P Value Welch t-test |
|---|---|---|---|---|
| Pseudomonas fluorescens (G−) | 53 (91%) | 42 (89%) | 11 (100%) | 0.02 |
| Cupriavidus metallidurans (G−) | 44 (76%) | 36 (77%) | 8 (73%) | 0.81 |
| Malassezia globosa | 32 (55%) | 22 (47%) | 10 (91%) | 8.9E-04 |
| Pseudomonas putida (G−) | 30 (52%) | 22 (47%) | 8 (73%) | 0.12 |
| Campylobacter coli (G−) | 27 (47%) | 27 (57%) | 0 (0%) | 4.4E-10 |
| Pseudomonas protegens (G−) | 26 (45%) | 18 (38%) | 8 (73%) | 0.05 |
| Campylobacter jejuni (G−) | 24 (41%) | 24 (51%) | 0 (0%) | 1.2E-08 |
| Enterococcus faecium (G+) | 22 (38%) | 22 (47%) | 0 (0%) | 8.3E-08 |
| Corynebacterium jeikeium (G+) | 22 (38%) | 20 (43%) | 2 (18%) | 0.10 |
| Alternaria alternata | 22 (38%) | 16 (34%) | 6 (55%) | 0.25 |
| Escherichia coli (G−) | 21 (36%) | 12 (26%) | 9 (82%) | 8.6E-04 |
| Pseudomonas aeruginosa (G−) | 21 (36%) | 11 (23%) | 10 (91%) | 4.8E-06 |
| Citrobacter freundii (G−) | 20 (34%) | 14 (30%) | 6 (55%) | 0.17 |
| Ralstonia pickettii (G−) | 20 (34%) | 12 (26%) | 8 (73%) | 0.01 |
| Staphylococcus epidermidis(G+) | 19 (33%) | 13 (28%) | 6 (55%) | 0.14 |
| Corynebacterium simulans (G+) | 18 (31%) | 15 (32%) | 3 (27%) | 0.77 |
| Corynebacterium striatum (G+) | 18 (31%) | 15 (32%) | 3 (27%) | 0.77 |
| Corynebacterium aurimucosum (G+) | 16 (28%) | 13 (28%) | 3 (27%) | 0.98 |
| Klebsiella pneumoniae (G−) | 15 (26%) | 10 (21%) | 5 (45%) | 0.18 |
| Pseudomonas mosselii (G−) | 15 (26%) | 6 (13%) | 9 (82%) | 1.4E-04 |
| Corynebacterium diphtheriae (G+) | 14 (24%) | 11 (23%) | 3 (27%) | 0.81 |
| Corynebacterium ureicelerivorans (G+) | 11 (19%) | 7 (15%) | 4 (36%) | 0.21 |
| Toxoplasma gondii | 10 (17%) | 7 (15%) | 3 (27%) | 0.43 |
| Bacteroides vulgatus (G−) | 10 (17%) | 5 (11%) | 5 (45%) | 0.06 |
| Aeromonas hydrophila (G−) | 9 (16%) | 6 (13%) | 3 (27%) | 0.35 |
| Corynebacterium riegelii (G+) | 7 (12%) | 5 (11%) | 2 (18%) | 0.57 |
| Corynebacterium urealyticum (G+) | 7 (12%) | 5 (11%) | 2 (18%) | 0.57 |
| Bacillus licheniformis (G+) | 6 (10%) | 6 (13%) | 0 (0%) | 0.01 |
G+, Gram-positive; G, Gram-negative.