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. 2020 Jul 8;61(8):9. doi: 10.1167/iovs.61.8.9

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Figure 6. — fRPE + MSC cell cotransplantation suppresses the expression of Iba1 and f4/80 and increases the nerve growth factor and brain-derived nerve growth factor expression in NaIO₃-induced retinopathy. (A) The expression level of Iba1 and F4/80 microglial factors significantly decreased in the fRPE + MSC cotransplantation group. ^&&& P < 0.001 versus wild type; ^** P < 0.01, ^*** P < 0.001 versus RDD model group; ^### P < 0.001 versus fRPE group (n = 6). (B) The expression level of nerve growth factor and brain-derived nerve growth factor neurotrophic factors significantly increased in all cell transplantation groups 1 month after the cell transplantation, especially in the fRPE + MSC cotransplantation group. ^&&& P < 0.001 versus wild type; ^** P < 0.01, ^*** P < 0.001 versus RDD model group; ^### P < 0.001 versus fRPE group (n = 6).