Table 3.

Summary of Frequency of RPE Morphology Within the GA Border

RPE Morphology*	Description*	Frequency of Distribution (%)†
Very Nonuniform	Slightly nonuniform morphology and pigmentation	48.84
Sloughed	Intact epithelium with spherical cells sloughed into subretinal space	32.56
Shedding	Intact epithelium with basal shedding of nonnucleated granule aggregates into BLamD	19.77
Bilaminar	Double layers	9.30
Intraretinal	Intraretinal	3.49
Dissociated	Nucleated non-contacting, individual RPE	37.21

^*Terms and descriptions defined in Zanzottera et al. 2015 [24].

^†Frequency calculated from all the quantified RPE phenotype in both epon-embedded and cryosections within 200 µm of the GA border. A total of 86 different regions in all 32 eyes from AMD donors were analyzed.