Figure 3.

(A) Lens of rat anterior segment were analyzed with the Pentacam system. (B) At P3. lens density of all MNU-treated groups was not significantly different from that of the control group. In the 70-mg/kg group, mean density began to increase at P7 and continued to increase until P21. (C) From P1 to P14, lens thickness in all MNU-treated groups was not significantly different from that in the control group. Mean thickness in the 70-mg/kg group was significantly higher than that in the control group and the 50- and 60-mg/kg groups at P21. Mean density and thickness in the 50- and 60-mg/kg groups were not significantly different from those in controls at all time-points (2-way ANOVA followed by Tukey's multiple-comparisons test, **** P < 0.0001,** P < 0.01* P < 0.05; n = 10; all values represent mean ± SEM.)