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. 2020 Jul 27;61(8):35. doi: 10.1167/iovs.61.8.35

Table 2.

Univariable and Multivariable Cox Analysis of Progressive Peripapillary RNFL or Macular GCIPL Thinning

Univariable Cox Analysis Multivariable Cox Analysis
Hazard Ratio 95% CI P Hazard Ratio 95% CI P
Age, years 1.001 0.984–1.018 0.921
Hypertension 1.612 0.960–2.707 0.071
Diabetes mellitus 1.971 1.062–3.656 0.031 1.998 1.067–3.742 0.031
Central corneal thickness (µm) 0.999 0.9991–1.006 0.736
Disc hemorrhage 2.191 1.309–3.667 0.003 2.116 1.260–3.555 0.005
RNFL thickness, µm 1.013 0.986–1.040 0.353
GCIPL thickness, µm 0.987 0.943–1.034 0.584
Mean deviation, dB 0.977 0.915–1.044 0.500
Axial length, mm 0.967 0.780–1.198 0.758
Disc torsion, degrees 0.982 0.950–1.015 0.279
Disc tilt ratio 1.250 0.485–3.222 0.644
Baseline IOP, mm Hg 0.968 0.865–1.083 0.566
Mean IOP, mm Hg 0.982 0.843–1.145 0.820
SD IOP, mm Hg 1.798 1.034–3.127 0.038 1.417 0.794–2.532 0.239
Peak IOP, mm Hg 1.028 0.911–1.160 0.656
Mean SBP, mm Hg 0.965 0.943–0.987 0.002
Minimum SBP, mm Hg 0.963 0.942–0.984 0.001 0.968 0.947–0.990 0.005
Maximum SBP, mm Hg 0.984 0.965–1.004 0.119
SD SBP, mm Hg 1.011 0.955–1.071 0.709
Mean DBP, mm Hg 0.956 0.924–0.990 0.012
Maximum DBP, mm Hg 0.979 0.951–1.007 0.132
Minimum DBP, mm Hg 0.967 0.943–0.991 0.007
SD DBP, mm Hg 1.009 0.931–1.094 0.826
MAP, mm Hg 0.954 0.925–0.985 0.004
MOPP, mm Hg 0.934 0.891–0.980 0.005
SPP, mm Hg 0.966 0.945–0.988 0.003
DPP, mm Hg 0.957 0.924–0.991 0.014

Indicated in bold type, P < 0.05 indicates statistical significance. CI, confidence interval.