Table 1.

APOE Allelic Association With POAG, HTG, and NTG

	NEIGHBOR
Allele	POAG(2120 Cases, 2262 Controls)		HTG(978 Cases, 2262 Controls)		NTG(395 Cases, 2262 Controls)
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
ε2	0.96 (0.83–1.13)	0.65	0.94 (0.77–1.15)	0.57	1.09 (0.83–1.42)	0.52
ε4	0.84 (0.74–0.96)	0.0078	0.81 (0.68–0.97)	0.013	0.69 (0.54–0.88)	0.0036
LRT		0.021		0.03		0.0099
	MEEI
	POAG(486 Cases, 344 Controls)		HTG(320 Cases, 344 Controls)		NTG(166 Cases, 344 Controls)
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
ε2	1.08 (0.74–1.60)	0.68	1.18 (0.77–1.79)	0.45	0.94 (0.54–1.59)	0.82
ε4	0.81 (0.60–1.10)	0.18	0.81 (0.58–1.13)	0.22	0.81 (0.53–1.20)	0.30
LRT		0.39		0.38		0.55
	Combined data set
	POAG(2606 Cases, 2606 Controls)		HTG(1298 Cases, 2606 Controls)		NTG(561 Cases, 2606 Controls)
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
ε2	0.97 (0.84–1.12)	0.70	0.98 (0.81–1.17)	0.80	1.01 (0.80–1.28)	0.92
ε4	0.83 (0.74–0.94)	0.0022	0.81 (0.70–0.94)	0.0052	0.71 (0.58–0.87)	0.0014
LRT		0.0067		0.02		0.0041