Fig 3. Effects on the EMG amplitudes during the CS.

(A) The averaged EMG amplitude over the first 250 ms of CS, expressed as a percentage of that averaged over 300 ms before the CS onset, in cued (circles) and non-cued (triangles) trials in (a) vehicle-injected control (n = 8) and (b) VU0255035-treated (n = 8) groups. (B) The differences in the averaged EMG amplitudes between cued and non-cued trials in control (squares) and VU0255035-treated (diamonds) groups. Empty and closed symbols represent the administration of the vehicle (denoted as vehicle (+)) and VU0255035 (marked as VU0255035 (+)), respectively. The vertical bars indicate the standard error of the mean.