| Risk of disease/event |
| • in a healthy patient with an unknown risk, e.g. CVD, cancer |
| • in an unborn child or embryo |
| Risk of recurrence of disease/event |
| • in a patient already diagnosed with e.g. CVD or cancer |
| Risk of deterioration of symptoms /condition/ quality of life |
| • in a patient with a chronic condition e.g. Chronic kidney disease, cancer |
| Risk of dying and end-of life |
| • in a frail patient or one with a chronic condition e.g. chronic kidney disease, cancer |
| Risk of side effects of treatment |
| • in invasive treatment such as surgery |
| • in patients with acute or chronic disease |
| Risk of treatment or diagnostic burden |
| • e.g. in surgery, drug treatment with high number of doses per day |
| • e.g. in invasive, painful or frightening diagnostic procedure |
| Risk of overtreatment |
| • e.g. resuscitation in cardiac events |
| • e.g. screening for disease in healthy persons |
