Skip to main content
. 2020 Aug 13;15(8):e0236879. doi: 10.1371/journal.pone.0236879

Fig 1. Effects of SC extract on the LNCaP cell line.

Fig 1

LNCaP cells were treated with SC extract (0–100 μg/mL) for 72 h, and cell viability was determined by MTT assay, using EZ-Cytox Cell Viability assay kit. (A) Cell viability of SC extract. LNCaP cells were incubated in medium containing testosterone (1 μM), Finasteride (10 μM), Saw palmetto (100 μg/mL) or SC (25, 50 μg/mL) for 72 h. Then, cells were harvested and subjected to the western blot assay. (B) Representative western blot analysis of AR, PSA, and 5α-reductase type 2 in TP-induced BPH in vitro. (C, D, E) Relative densitometry evolution of AR, PSA, and 5α-reductase type 2, the western blot data respectively. Data are expressed as the means ± SD of three replicate experiments. ### p < 0.001 versus control group; *** p < 0.001 versus BPH group.