Table 1. Effect of SC extract on prostate and body weight in TP-induced BPH rats.
Body weight (g) | Prostate weight (g) | |||
---|---|---|---|---|
Initial | Final | Absolute | Relative | |
Control | 250.9 ± 9.51 | 378.9 ± 40.92 | 0.66 ± 0.08 | 1.00 ± 0.18 |
BPH | 230.9 ± 8.90 | 340.6 ± 23.12 | 1.25 ± 0.12### | 2.07 ± 0.23### |
Fina | 230.7 ± 8.22 | 348.0 ± 23.15 | 1.01 ± 0.06*** | 1.64 ± 0.22*** |
Saw | 230.8 ± 8.09 | 336.2 ± 22.75 | 1.24 ± 0.08 | 2.09 ± 0.17 |
SC 50 | 230.8 ± 7.73 | 346.8 ± 23.29 | 0.99 ± 0.14*** | 1.61 ± 0.21*** |
Abbreviations: Control (PBS, P.O.), BPH (5 mg/kg TP, S.C. + PBS, P.O.), Fina (5 mg/kg TP, S.C. + finasteride 10 mg/kg, P.O.), Saw (5 mg/kg TP, S.C. + saw palmetto 100 mg/kg, P.O.), SC 50 (5 mg/kg TP, S.C. + SC extract 50 mg/kg, P.O.). To induce BPH, all rats were received daily TP injection (5 mg/kg, S.C.) for consecutive 4 weeks, except for the control group. Data are expressed as the means ± SD (n = 6).
### p < 0.001 versus control group.
*** p < 0.001 versus BPH group.