Table 2. Summary of receiver operator characteristic results for the ALSFRS-R bulbar subscale and swallowing item to detect global pharyngeal dysphagia.
| Global Dysphagia | Bulbar Subscale: | Swallowing Item: | ||||||
|---|---|---|---|---|---|---|---|---|
| ≤11 | ≤10 | ≤9 | ≤8 | ≤7 | ≤3 | ≤2 | ≤1 | |
| Sensitivity | 87.1% | 76.7% | 68.1% | 50.9% | 34.5% | 68.1% | 20.7% | 3.4% |
| (95% CI) | (81.0, 93.2) | (69.0, 84.4) | (59.6, 76.6) | (41.8, 60.0) | (25.8, 43.1) | (59.6, 76.6) | (13.3, 28.1) | (0.1, 6.8) |
| Specificity | 33.3% | 48.1% | 67.9% | 84.0% | 93.8% | 64.2% | 93.8% | 100% |
| (95% CI) | (23.1, 43.6) | (37.3, 59.0) | (57.7, 78.1) | (76.0, 91.9) | (88.6, 99.1) | (53.8, 74.6) | (88.6, 99.1) | (100, 100) |
| PPV | 65.2% | 67.9% | 75.2% | 81.9% | 88.9% | 73.1% | 82.2% | 100% |
| (95% CI) | (57.7, 72.7) | (59.9, 75.9) | (67.0, 83.5) | (73.1, 90.8) | (79.7, 98.1) | (64.8, 81.5) | (69.0, 96.5) | (100, 100) |
| NPV | 64.3% | 59.1% | 59.8% | 54.4% | 50.0% | 58.4% | 45.2% | 42.0% |
| (95% CI) | (49.8, 78.8) | (47.2, 71.0) | (49.8, 69.8) | (45.7, 63.1) | (42.1, 57.9) | (48.2, 68.7) | (37.7, 52.8) | (35.0, 48.9) |
| AUC: | 0.73 | 0.68 | ||||||
(CI, confidence interval, PPV, positive predictive value. NPV, negative predictive value, AUC, area under curve.)