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. 2020 Aug 13;15(8):e0237442. doi: 10.1371/journal.pone.0237442

Fig 3. SB203580 reduces while IL-6 promotes the proliferation of Plum-AD and PLum-AI cells in a time-dependent manner.

Fig 3

(A) Representative bright-field images of PLum-AD and PLum-AI cells showing effect of treatment with SB203580 (10 μM) or IL-6 (10 ng/mL) on cell proliferation and morphology. Scale = 100μm. After incubation of cells for 24, 48 and 72 hours with or without treatment with SB203580 or IL-6, cell proliferation was determined using MTT assay. (B) Results are expressed as percentage of proliferation of the treated group compared to control at every time point. Data represents an average of three independent experiments and is reported as mean ± SEM (Two-way ANOVA with Bonferroni’s corrected test for multiple comparisons *P < 0.05; **P < 0.01; ***P < 0.001).