Skip to main content
. 2020 Aug 13;15(8):e0234492. doi: 10.1371/journal.pone.0234492

Fig 3. Effects of sFlt-1 and Z-LEHD-FMK on the vascular injury marker of vWF.

Fig 3

The HUVECs were treated with the indicated concentrations of sFlt-1, and then treated with or without Z-LEHD-FMK. The histogram showed that vWF expression were significantly upregulated by sFlt-1 stimulation at 1000 ng/ml (11.50 ± 1.39 vs. 6.31 ± 2.07 ng/ml, p = 0.023) compared with those of untreated cells, whereas the expression of vWF was down-regulated after added with Z-LEHD-FMK (11.50 ± 1.39 vs. 7.39 ± 1.78 ng/ml, p = 0.015). Results are the means ± standard deviation of three independent experiments.