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. 2020 Aug 13;15(8):e0234492. doi: 10.1371/journal.pone.0234492

Fig 7. JC-1 monomer increased with the stimulation of sFlt-1 and decreased after administration of Z-LEHD-FMK in HUVECs.

Fig 7

A: Effect of Z-LEHD-FMK on sFlt-1-induced disruption of mitochondrial membrane potential in HUVECs. B: statistical result of the percentage of JC-1 monomer in different groups. HUVECs with low ΔΨm increased from 7.63% in untreated cells to 21.33% in cells treated with 100 ng/ml sFlt-1, and further increased to 24.5% in cells with 1000 ng/ml sFlt-1. These effects were alleviated by addition of Z-LEHD-FMK.