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. 2020 Jul 7;19(8):2942–2949. doi: 10.1021/acs.jproteome.9b00706

Figure 5.

Figure 5

Composition of head groups of a phospholipid bilayer of a cellular membrane. Choline and ethanolamine are two main substrates for the synthesis of phosphatidylcholine (PtC) and phosphatidylethanolamine (PtE), respectively. PtC can be degraded via GPC to choline. Proteins embedded in the cellular membrane are shown to be glycosylated. Abbreviations: ADP, adenosine diphosphate; ATP, adenosine triphosphate; CDP, cytidine diphosphate; CKI 1, choline kinase; CTP, cytidine triphosphate; ECT phosphoethanolamine cytidylyltransferase; EK, ethanolamine kinase; EPT, ethanolaminephosphotransferase; LPL, lysophospholipase; P-Eta, phosphoethanolamine; P-choline, phosphocholine; PD, glycerophosphocholine phosphodiesterase; PLA, phospholipase A2; and PPi, pyrophosphate.