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. 2020 Aug 7;13:61–76. doi: 10.2147/NSA.S257392

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© 2020 Salado-Leza et al.

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(A) Schematic representation of the Nano-SIMS principle. Nano-SIMS images of a HeLa cell loaded with PtPEG NPs. Panels correspond to the intracellular location of (B) P⁻ and (C) ¹⁹⁴Pt⁻. (D) Merged image of ¹⁹⁴Pt⁻ and P⁻. The arrow points out the location of NPs in the cell cytoplasm.