Table 4. Allele frequencies found in the studied population compared to allele frequencies of populations in the HapMap study (Caucasian and African origins). Ribeirão Preto, SP, Brasil, 2016.
Polymorphism | Alele | n* | RP(%)† | CEU(%)‡ | YRU(%)§ | Pa‖ | Pb¶ |
---|---|---|---|---|---|---|---|
CYP2C9 * 2 (rs1799853) | *1 | 119 | 88.8 | 89.6 | 100 | - | - |
*2 | 15 | 11.1 | 10.4 | 0 | 0.818 | <0.001* * | |
CYP2C9 * 3 (rs1057910) | *1 | 124 | 92.5 | 94.2 | 100 | - | - |
*3 | 10 | 7.5 | 5.8 | 0 | 0.774 | 0.007* * |
n = Values in number of observations;
RP = Population of Ribeirão Preto, São Paulo;
CEU = caucasian europeans - population of Caucasian origin composed of descendants of Europeans who inhabit the Utah region in the United States (USA);
YRU = Yorubans - population of African origin from the Yoruba ethnic group, inhabitants of Ibadan, Nigeria;
Pa = p-value of the comparison between populations RP vs. CEU;
Pb = p-value of the comparison between populations RP vs. YRU;
Statistically significant