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. 2020 Aug 12;5(4):e00535-20. doi: 10.1128/mSphere.00535-20

TABLE 3.

A. fumigatus allergens exposed to the surface

Allergena Protein description No. of AAs Detected in the samples Biotinylation site(s)b
Asp f 1 Mitogillin 176 G K96G; K138G; K140G
Asp f 2 Allergen Asp f 2 314 M K83M
Asp f 4 Allergen Asp f 4 322 S, M K140S,M; K155 or 156M; K220M; K306M
Asp f 6 (Sod3) Putative manganese superoxide dismutase 210 G, M K50G; K59G; K88G,M; K93G,M; K101G; K202M
Asp f 9 Cell wall glucanase 395 S, M K190S,M
Asp f 11 (Cyp4) Putative cyclophilin 205 S K119S
Asp f 12 (Hsp90) Heat shock protein 706 G K481G
Asp f 17 (Mp1)c Putative cell wall galactomannoprotein 284 D K63D; K144D
Asp f 18 (Alp2) Autophagic (vacuolar) serine protease 495 D K261D; K268D; K271D; K291D
Asp f 23 (RpL3) Allergenic ribosomal L3 protein 392 M K5M
Asp f 27c Putative peptidyl-prolyl cis-trans isomerase; cyclophilin 163 D, S, G K43D,S; K140D,S,G; K152 or K153D
Asp f 28c Putative thioredoxin 171 M K125M
Asp f mannosidase (MsdS)c Putative 1,2-alpha-mannosidase 503 D K212D; K274D; K415D; K416D; K488D
Asp f catalase (Cat1)c Catalase 728 D K261D; K346D; K466D
Asp f glucosidase (Exg12)c Secreted beta-glucosidase 863 D, M K127D; K178D; K415D; K603D; K839D; K843D,M
Asp f FDH Putative NAD-dependent formate dehydrogenase 418 G, M K304M; K319G; K327M
Asp f MDHc Putative NAD-dependent malate dehydrogenase 340 S, G, M K91G; K185 or K186M; K238S,G,M; K263S,G,M; K269G; K303G; K309G,M; K327M; K331M
Asp f GT (Gel2) GPI-anchored 1,3-beta-glucanosyltransferase 475 S, M K36M; K187M; K372M; K379S,M; K388M; K393M
Asp f gamma_Actin (Act1)c Actin 393 M K346M
Asp f RPS3c 40S ribosomal protein S3 266 M K78M
a

A. fumigatus allergens based on allergome website (www.allergome.org).

b

Lysine residues of the protein detected with biotinylation marks in dormant (D), swollen (S), or germinating (G) conidia and hyphae (M) are indicated.

c

Allergens commonly detected in different surface proteomics data; see also Table 5.