Fig. 7.

Inhibitory effects of DEA/NO and PGE1 on ADP-induced aggregation in RT or cold-stored PB samples. Light transmission aggregation was performed with PRP of stored PB samples as indicated. The results are shown as mean % ± SEM and represent the relative inhibition of 10 µM ADP-induced aggregation in relation to the corresponding PB samples without DEA/NO or PGE1 incubation (as 0% inhibition); n  = 6; * p  < 0.05, ^# p  < 0.1 (compared as indicated; blue: RT-APC to C-APC). ADP, adenosine diphosphate; C-APC, cold-stored apheresis-derived platelet concentrates; DEA/NO, diethylamine NONOate; PB, peripheral blood; PGE1, prostaglandin E1; RT, room temperature; SEM, standard error of mean.