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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Neurol. 2020 May 9;267(9):2603–2611. doi: 10.1007/s00415-020-09883-4

Table 1:

Baseline demographic and clincial characteristics of the PAOS patients

Variables All PAOS (n=17) PAOS− (n=12) PAOS+ (n=5) p-value
Sex [M] 8 (47%) 3 (25%) 5 (100%) 0.005*
Handedness [R] 16 (94%) 12 (100%) 4 (80%) 0.11
Education, yrs. 16 (13–18) 16 (12.5–17.5) 16 (12.5–19) 0.55
Age at onset, yrs. 70 (63–73) 70 (62.5–73) 65 (55–78) 0.83
Age at DAT scan, yrs. 73 (64–75) 73 (63–75) 69 (61–81) 0.75
Disease duration, yrs. 3 (1.5–5) 3 (1–5) 4 (1.5–7) 0.53
UPDRS-I/52 7 (3.5–8) 6 (4–8) 7 (1.5–10.5) 0.96
UPDRS-II/52 3 (2.5–7) 3 (2.25–7.25) 4 (2.5–8) 0.67
UPDRS-III/132 11 (9–21.5) 11.5 (10–22.75) 11 (6.5–19.5) 0.56
FBI/72 10 (7.5–19.5) 9 (6.25–11.75) 18 (10.5–26) 0.10
Limb apraxia score/60 58 (52–59) 58 (51.5–58) 59 (53.5–59) 0.33
TRAILS-A MOANS 8 (6–11.75) 8 (6–11.75) 7.5 (4.5–12) 0.85
ASRS-3 total 19 (11–23.75) 14 (10–24) 23 (14–23.5) 0.5
Aphasia 12 (71%) 8 (67%) 4 (80%) 0.58
AOS type (phonetic/prosodic)# 7(41%)/4(24%) 5(42%)/3(25%) 2 (40%)/1(20%) 0.96
MoCA/30 25 (19–26) 24 (19–27) 25 (18–28) 0.91
WAB-AQ/100 96 (92.5–97.6) 95 (92.5–97.5) 97 (81–99) 0.4
PSIS/5 1 (0–1) 0.5 (0–1) 1 (0.5–1.5) 0.3
PSP-RS/100 12 (7–17) 11 (7–18.5) 12 (6–19.5) 0.9
PSP-GM/20 1 (0–3) 1 (0–2.75) 0 (0–3.5) 0.8
*

Statistically significant.

#

Remaining cases had mixed features of both prosodic and phonetic

Data for sex, handedness, aphasia, and AOS type summarized as numbers (percentages) and for all other variables summarized as median (interquartile ranges). [M] represents male sex.

PAOS− means PAOS patients with normal DAT scan, PAOS+ means PAOS patients with abnormal DAT scan.