Table 2:
Comparison of demographic and DAT measures in PAOS, CBS, and PSP patients
| Variables | PAOS− (n=12) | PAOS+ (n=5) | CBS (n=8) | PSP (n=15) | PAOS+ vs. PAOS− p-value | PAOS+ vs. CBS p-value | PAOS+ vs. PSP p-value |
|---|---|---|---|---|---|---|---|
| Sex [M] | 3 (25) | 5 (100) | 2 (25) | 6 (40) | 0.04* | 0.07 | 0.12 |
| Age at onset | 70 (62.5, 73) | 65 (55, 78) | 54 (49,62) | 64 (56, 66) | 1 | 0.5 | 0.82 |
| Age at DAT scan | 73 (63, 75) | 69 (61, 81) | 60 (57, 64) | 66 (62, 71) | 0.99 | 0.41 | 0.72 |
| Disease duration | 3 (1, 5) | 4 (1.5, 7) | 3 (1.5, 8) | 2 (1, 3) | 0.94 | 1 | 0.86 |
| Right anterior Putamen | 1.89 (1.73, 2.42) | 1.33 (0.88, 1.73) | 1.57 (0.90, 1.82) | 0.82 (0.60, 1.08) | 0.08 | 0.99 | 0.22 |
| Left anterior Putamen | 1.8 (1.62, 2.40) | 1.30 (0.97, 1.44) | 1.55 (1.05, 2.1) | 0.8 (0.50, 0.94) | 0.01* | 0.7 | 0.07 |
| Right posterior putamen | 1.70 (1.38, 2.28) | 1.21 (0.66, 1.50) | 1.36 (0.53, 1.70) | 0.59 (0.35, 0.70) | 0.17 | 0.99 | 0.10 |
| Left posterior Putamen | 1.68 (1.42, 2.33) | 1.04 (0.90, 1.18) | 1.25 (0.63, 1.91) | 0.42 (0.30, 0.56) | 0.05* | 0.98 | 0.03* |
| Right caudate | 2.63 (2.2, 2.70) | 1.48 (1.40, 2.30) | 1.94 (1.11, 2.13) | 1.24 (0.75, 1.55) | 0.17 | 0.99 | 0.18 |
| Left caudate | 2.25 (2.10, 2.64) | 1.73 (1.42, 2.17) | 1.86 (1.54, 2.54) | 1.18 (0.70, 1.29) | 0.13 | 0.91 | 0.08 |
| Right anterior putamen/caudate ratio | 0.84 (0.75, 0.88) | 0.73 (0.62, 0.84) | 0.82 (0.78, 0.87) | 0.71 (0.60, 0.83) | 0.55 | 0.69 | 0.99 |
| Left anterior putamen/ caudate ratio | 0.80 (0.76, 0.90) | 0.75 (0.57, 0.83) | 0.79 (0.68, 0.84) | 0.71 (0.61, 0.78) | 0.42 | 0.85 | 0.99 |
| Right posterior putamen/caudate ratio | 0.72 (0.63, 0.85) | 0.57 (0.47, 0.81) | 0.70 (0.46, 0.82) | 0.48 (0.31, 0.67) | 0.55 | 0.96 | 0.90 |
| Left posterior putamen/ caudate ratio | 0.79 (0.66, 0.85) | 0.58 (0.46, 0.80) | 0.65 (0.41, 0.76) | 0.43 (0.31, 0.70) | 0.68 | 1 | 0.61 |
| Anterior putamen absolute difference | 0.12 (0.08, 0.26) | 0.27 (0.24, 0.37) | 0.12 (0.03, 0.23) | 0.12 (0.08, 0.19) | 0.23 | 0.14 | 0.1 |
| Posterior putamen absolute difference | 0.13 (0.04, 0.18) | 0.34 (0.22, 0.41) | 0.14 (0.03, 0.32) | 0.18 (0.07, 0.35) | 0.06 | 0.41 | 0.26 |
| Caudate absolute difference | 0.28 (0.12, 0.32) | 0.24 (0.13, 0.37) | 0.29 (0.05, 0.53) | 0.16 (0.11, 0.23) | 0.96 | 0.88 | 0.22 |
*
Statistically significant
Data for sex summarized as numbers (percentages) and for all other variables summarized as median (interquartile ranges). [M] represents the male sex.
PAOS− means PAOS patients with normal DAT scan, PAOS+ means PAOS patients with abnormal DAT scan