Table 1.
Anthropometric data and baseline laboratory parameters
| Control subjects (n = 10) | PKU subjects (n = 12) | p | |
|---|---|---|---|
| Age (years) | 26 (24.7–27) | 26 (20.2–36.7) | 0.958 |
| Height (cm) | 181 (175.6–184.3) | 179.3 (174.6–183.5) | 0.615 |
| Weight (kg) | 74.7 (66.4–87.7) | 69.5 (65.8–80) | 0.221 |
| BMI (kg/m2) | 22.5 (21.6–26.7) | 23.15(20.3–25.2) | 0.710 |
| Body fat (%) | 16.6 (13.8–20.9) | 16.1 (11.9–25.5) | 0.909 |
| Body muscle (%) | 47.3 (45.3–48.5) | 47.5 (42.1–49.3) | 0.497 |
| Body bone (%) | 4.6 (4.4–4.8) | 4.5 (4–4.8) | 0.328 |
| Residual (%) | 31.3 (29.1–32.5) | 31.3 (29.1–32.5) | 0.949 |
| Resting HR (beats/min) | 68.5 (57.2–76) | 63 (56.2–73.7) | 0.685 |
| Resting systolic BP (mmHg) | 123.5 (118.5–126.5) | 119.5 (110.5–123.8) | 0.178 |
| Resting diastolic BP (mmHg) | 69.5 (64.5–74.2) | 66.5 (64.2–70) | 0.328 |
| Phe (μmol/L) | 43.4 (39.7–58.7) | 562.1 (361.8–727.3) | < 0.001 |
| Tyr (μmol/L) | 47.4 (42.0–55.7) | 39.4 (32.5–79.9) | 0.719 |
| NE (pg/ml) | 344.4 (191.1–414.5) | 224.1 (201–265) | 0.203 |
| E (pg/ml) | 27.4 (21.7–38.9) | 34.2 (30.3–41.1) | 0.274 |
Values are presented as median (25th and 75th percentiles)
Abbreviations: HR heart rate, BP blood pressure, Phe phenylalanine, Tyr tyrosine, NE norepinephrine, E epinephrine