Table 2.

Blood pressure, heart rate, and laboratory parameters during cold pressor test

	Control subjects (n = 10)	PKU subjects (n = 12)	p
∆ HR (beats/min)	25 (17–32)	21.5 (14–30.5)	0.473
∆ Systolic BP (mmHg)	16 (5.5–23)	16.5 (14–24.7)	0.472
∆ Diastolic BP (mmHg)	12 (4.5–20)	15.5 (8.5–17.7)	0.638
∆ Phe (μmol/L)	0.8 (− 2.7–2.0)	7.3 (− 12.9–48.7)	0.764
∆ Tyr (μmol/L)	0.4 (− 5.5–3.1)	3.2(− 1.6–11.6)	0.211
∆ NE (pg/ml)	61.6 (22.3–190.5)	81.9 (31.8–103.4)	0.915
∆ E (pg/ml)	10.9 (7.4–45.4)	17.9 (8.7–53.8)	0.680

Values are presented as median (25th and 75th percentiles)

Abbreviations: ∆ change from resting, HR heart rate, BP blood pressure, Phe phenylalanine, Tyr tyrosine, NE norepinephrine, E epinephrine