Table 3.

Blood pressure, heart rate, and laboratory parameters during isometric handgrip test

	Control subjects (n = 10)	PKU subjects (n = 12)	p
∆ HR (beats/min)	20 (15–24)	16 (12.2–25.2)	0.491
∆ Systolic BP (mmHg)	23.5 (7.7–48.2)	36.5 (19–43.5)	0.261
∆ Diastolic BP (mmHg)	18 (10–40)	13.5 (4.7–19.5)	0.371
∆ Phe (μmol/L)	2.7 (− 1.3 – 5.9)	11.1 (−33.5–37)	0.242
∆ Tyr (μmol/L)	0.4 (− 5.5–3.1)	− 1.4 (− 8.2–0.9)	0.645
∆ NE (pg/ml)	61.2 (34.0–209.5)	40.6 (17.7–98.8)	0.999
∆ E (pg/ml)	14.5 (5.4–53.5)	14.2 (4.9–27.6)	0.541

Values are presented as median (25th and 75th percentiles)

Abbreviations: ∆ change from resting, HR heart rate, BP blood pressure, Phe phenylalanine, Tyr Tyrosine, NE norepinephrine, E epinephrine