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. 2020 Mar 12;77(17):3311–3323. doi: 10.1007/s00018-020-03487-x

Table 5.

Expression of SLC6A14 in other diseases

Disease SLC6A14 expression Methods Ref
Cancer Cervical Up-regulated PCR, IF/IH, HIS [54]
Colorectal Up-regulated PCR, Northern blot, IH [55]
Pancreatic Up-regulated Microarray, qPCR, WB, IF, IH [56, 57]
Breast (ER +) Up-regulated PCR, IF [58]
Colonic diseases Crohn’s disease Up-regulated qPCR [46]
Ulcerative colitis Up-regulated qPCR, microarray [41, 59, 60]
Long vs. short duration of ulcerative colitis Down-regulated Microarray [61]
Ischemic or infectious colitis Up-regulated qPCR [60]
Cholera Acute vs. convalescence phase Up-regulated Microarray, qPCR, IH [42]
IPF IPF Down-regulated scRNAseq [36]
IPF vs. NSIP Up-regulated Microarray [62]

ER+ estrogen receptor-positive, IPF idiopathic pulmonary fibrosis, NSIP non-specific interstitial pneumonia. If not specifically mentioned, the expression of SLC6A14 is relative to control patients. IF immunofluorescence, IH immunohistochemistry, HIS hybridization in situ, PCR polymerase chain reaction, WB western blot