Table 5.
Disease | SLC6A14 expression | Methods | Ref | |
---|---|---|---|---|
Cancer | Cervical | Up-regulated | PCR, IF/IH, HIS | [54] |
Colorectal | Up-regulated | PCR, Northern blot, IH | [55] | |
Pancreatic | Up-regulated | Microarray, qPCR, WB, IF, IH | [56, 57] | |
Breast (ER +) | Up-regulated | PCR, IF | [58] | |
Colonic diseases | Crohn’s disease | Up-regulated | qPCR | [46] |
Ulcerative colitis | Up-regulated | qPCR, microarray | [41, 59, 60] | |
Long vs. short duration of ulcerative colitis | Down-regulated | Microarray | [61] | |
Ischemic or infectious colitis | Up-regulated | qPCR | [60] | |
Cholera | Acute vs. convalescence phase | Up-regulated | Microarray, qPCR, IH | [42] |
IPF | IPF | Down-regulated | scRNAseq | [36] |
IPF vs. NSIP | Up-regulated | Microarray | [62] |
ER+ estrogen receptor-positive, IPF idiopathic pulmonary fibrosis, NSIP non-specific interstitial pneumonia. If not specifically mentioned, the expression of SLC6A14 is relative to control patients. IF immunofluorescence, IH immunohistochemistry, HIS hybridization in situ, PCR polymerase chain reaction, WB western blot