Table 1.

Baseline health-related quality of life in subgroups defined by depressive symptom severity and duration

	Sertraline (n = 324)	Placebo (n = 329)	Overall (n = 653)
	Mean (SE)	Mean (SE)	Mean (SE)
Severity subgroups
EQ5D-5L
Mild (n = 129)	0.816 (0.014)	0.796 (0.017)	0.806 (0.011)
Moderate (n = 173)	0.769 (0.016)	0.800 (0.012)	0.785 (0.010)
Severe (n = 349)	0.652 (0.016)	0.653 (0.016)	0.653 (0.011)
PHQ-9
Mild (n = 128)	5.657 (0.410)	6.049 (0.548)	5.844 (0.337)
Moderate (n = 173)	9.500 (0.432)	10.258 (0.420)	9.890 (0.302)
Severe (n = 350)	15.308 (0.370)	15.275 (0.349)	15.291 (0.254)
Duration subgroups
EQ5D-5L
< 2 years (n = 439)	0.729 (0.012)	0.743 (0.012)	0.736 (0.009)
≥ 2 years (n = 212)	0.690 (0.020)	0.673 (0.020)	0.681 (0.014)
PHQ-9
< 2 years (n = 438)	11.408 (0.400)	11.550 (0.388)	11.479 (0.278)
≥ 2 years (n = 213)	12.600 (0.567)	13.519 (0.521)	13.066 (0.385)